Can Metformin Help with Fertility?

What is Metformin?

For those suffering from type 2 diabetes, metformin is an essential FDA-approved medication used to help control their high blood sugar levels. Metformin is a drug that helps to decrease the levels of glucose that the body absorbs from its food intake, ultimately having a direct impact on the amount of sugar entering our body’s bloodstream, as well. Metformin plays a critical role not only in managing blood sugar levels, but in the aftermath effects of high blood sugar such as blindness, problems with nerves, kidney damage, and overall sexual function. However, for optimum benefits, it’s recommended that metformin is used in combination with a proper exercise program and diet! According to WebMD, overall metformin helps to restore the body’s response to the insulin it naturally produces while decreasing the amount of sugar your body absorbs and your liver produces.

Although metformin is commonly discussed in terms of type 2 diabetes treatment, other unique benefits of the drug are frequently overlooked. Metformin may also help improve fertility in patients. For those suffering from type 2 diabetes, pre-diabetes, or even PCOS, they oftentimes also deal with impaired fertility and other fertility-related issues. But how exactly does metformin help to improve fertility in users? There are several unique fertility-related benefits associated with metformin’s use, such as those outlined below.

Benefits of Metformin on Fertility

Helps to Induce Ovulation

According to research published by The Journal of Clinical Endocrinology and Metabolism, metformin can help to improve ovulation for women, especially those suffering from PCOS, by improving their insulin sensitivity, reducing gluconeogenesis, and reducing overall androgen production. In fact, studies also found that when compared to a placebo, metformin had a direct impact on inducing ovulation for infertile women dealing with PCOS. This is primarily because women’s menstrual cycles become more regulated while on metformin, thus helping to induce ovulation in users.

Reduces Risks of Ovarian Hyperstimulation Syndrome (OHSS)

Ovarian Hyperstimulation Syndrome, otherwise known as OHSS, is another risk oftentimes correlated with infertility and infertility treatments such as ICSI or IVF. When patients are administered infertility drugs, they are put at a heightened risk of developing OHSS, especially women who have PCOS. However, according to the National Library of Medicine, metformin may be beneficial in combating OHSS by helping to reduce users’ typical increase in their body weight as well as circulating progesterone and estradiol and vascular permeability. In turn, patients can still receive their IVF or ICSI treatments and have a much lower risk of developing OHSS.

Reduces Weight

As mentioned previously, many women who deal with PCOS tend to put weight on much quicker and easier and are more prone to obesity or other weight-related health issues. Metformin, however, has been studied and suggested to help reduce weight in women, especially those suffering from Obese PCOS as mentioned above. As their weight levels decrease, their bodies are more able to properly ovulate, thus helping to increase their chances of a successful pregnancy.

Improvements in Male Reproduction

Outside of women alone, metformin has also been linked to improving males’ ability to reproduce. In fact, a study was carried out on 45 men who were suffering from metabolic syndrome. The men were prescribed metformin and took it over a 6-month period. Blood and semen samples were taken both before, and after the experiment was completed. The metformin helped to reduce the men’s insulin resistance and improve their semen quality.

Where Can I Buy Metformin?

Because of the unique benefits correlated with metformin’s use, it’s no surprise that it’s quickly gaining traction in today’s market. Metformin can be easily prescribed online from companies that specialize in prescription therapies such as AgelessRx. If you’re experiencing fertility issues revolving around your type 2 diabetes, pre-diabetes, PCOS, or metabolic syndrome, metformin may be a great fit for you! Learn more or consider seeking out a metformin prescription today!